Fundamentals of Anatomy and Physiology 12th Edition © 2024

Fundamentals of Anatomy and Physiology, published by Pearson, has enhanced its text and artwork to reflect how today’s students learn. The most recent research pairs with detailed illustrations to explain complex structures and functions.

  • Content aligned to diversity, equity, and inclusion to reflect students’ lived experiences
  • Holistic approach shows how body systems affect one another
  • New discussions around gender and reproduction in the genetics and human development chapters
  • This program is accompanied by Pearson’s Mastering® platform with eText

Anatomy & Physiology Curriculum with Digital Integration

Easy-to-understand narratives, clear visuals, and accurate content help students navigate the complicated aspects of A&P.


Building Connections

Macro-to-Micro Figures start with familiar structures of the human body before zooming in to reveal smaller and smaller components that might be lesser known but still provide a significant function.


Current and Future Concerns

Clinical Notes look at relevant topics including alcohol, sex and gender, and types of vaccinations. Broader discussions consider how those topics might play an important role in students’ careers.


Learning Through Narrative

Story-based Clinical Cases open each chapter to create interest in the upcoming material then conclude with a Clinical Case Wrap-Up that asks students to reflect on what they learned.


Practice Anatomy Lab™

Practice Anatomy Lab™ (PAL™ 4.0) is an indispensable virtual anatomy study and practice tool that gives students 24/7 access to the most widely used lab specimens including human cadavers, anatomical models, histology, cat, fetal pig, cow eye, and sheep heart and brain.

High School Anatomy & Physiology Teaching Solutions

  • Hallmark Features of the Program

  • New and Updated Features

Hallmark Features of the Program

  • Side-by-Side Figures

    Side-by-Side Figures provide multiple views of the same structure. Illustrations pair with cadaver photos to compare between how a body part is represented and what it actually looks like.

  • Step-by-Step Figures

    Step-by-Step Figures parallel the book’s narrative descriptions to illustrate multifaceted processes.

  • Build-Your-Knowledge Features

    Build-Your-Knowledge features show how each body system influences the others and how they work together to maintain homeostasis.


New and Updated Features

  • Brief and Concrete Learning

    Tips (formerly Tips & Tools) offer brief and concrete learning devices to help students remember facts and concepts. From simple analogies to easy memory tricks, students can develop their own strategies.


Take a Deeper Look at Fundamentals of Human Anatomy & Physiology



Get to know Fundamentals of Human Anatomy & Physiology with Mastering® A&P with Pearson eText.

Online Platform for your High School Anatomy & Physiology Course


Mastering® A&P offers instructors and students the resources and flexibility they need to understand the body and its systems with depth and clarity.

Next Generation Science Standards

Our solutions are designed to support and correlate to the Next Generation Science Standards.

View Correlation

More About Fundamentals of Human Anatomy & Physiology

  • Frederic (Ric) H. Martini, Ph.D. Author Bio

    Dr. Martini received his Ph.D. from Cornell University in comparative and functional anatomy for work on the pathophysiology of stress. In addition to professional publications that include journal articles and contributed chapters, technical reports, and magazine articles, he is the lead author of 10 undergraduate texts on anatomy and physiology.

    He has also published books on tropical islands, on WWII history, and in science fiction. Dr. Martini has a long-standing bond with the Shoals Marine Laboratory, a joint venture between Cornell University and the University of New Hampshire, where he received his undergraduate degree.

    He has been active in the Human Anatomy and Physiology Society (HAPS) for over 30 years and was a member of the committee that established the course curriculum guidelines for A&P. He is a President Emeritus of HAPS after serving as President-Elect, President, and Past-President over 2005–2007. Dr. Martini is also a member of the American Physiological Society, the American Association of Anatomists, the International Society of Vertebrate Morphologists, and the Society of Military History.

  • Judi L. Nath, Ph.D. Author Bio

    Dr. Judi Nath is an adjunct teaching professor at Penn State University and biology professor emerita at Lourdes University. She teaches both undergraduate and graduate students in courses including anatomy, physiology, pathophysiology, medical terminology, and science writing.

    She received her bachelor’s and master’s degrees from Bowling Green State University, which included study abroad at the University of Salzburg in Austria. Her doctoral work focused on auto-immunity, and she completed her Ph.D. from the University of Toledo. Dr. Nath is devoted to her students and strives to convey the intricacies of science in captivating ways that are meaningful, interactive, and exciting.

    She has won the Faculty Excellence Award—an accolade recognizing effective teaching, scholarship, and community service—multiple times and in 2013 was named as an Ohio Memorable Educator. She is active in many professional organizations, notably the Human Anatomy and Physiology Society (HAPS), where she is a past president and has served several terms on the board of directors.

    She is also the 2021 recipient of the HAPS President’s Medal. Dr. Nath is a coauthor of Visual Anatomy & Physiology, Visual Essentials of Anatomy & Physiology, Anatomy & Physiology, and Human Anatomy (published by Pearson); she is the sole author of Using Medical Terminology, Stedman’s Medical Terminology, and Short Course in Medical Terminology (published by Jones & Bartlett); Applied Pathophysiology (published by Lippincott), and Digesting Foods and Fads and Sins Against Science (published by McFarland).

    She is also a board member of America Cares for Ukrainian Children. In 2015, she and her husband established the Nath Science Scholarship at Lourdes University to assist students pursuing science-based careers. She is an aspiring tap dancer and dog trainer with goals of achieving a healthy work-life balance.

  • Edwin F. Bartholomew, M.S. Author Bio

    Edwin F. Bartholomew received his undergraduate degree from Bowling Green State University and his M.S. from the University of Hawaii. Mr. Bartholomew has taught human anatomy and physiology at both the secondary and undergraduate levels.

    In addition, he has taught courses ranging from botany to zoology at Maui Community College (now the University of Hawaii Maui College). For 17 years, he taught at historic Lahainaluna High School, the oldest high school west of the Rockies, where he assisted in establishing a Health Occupations Students of America (HOSA) chapter.

    He is a coauthor of Fundamentals of Anatomy & Physiology, Visual Anatomy & Physiology, Essentials of Anatomy & Physiology, Visual Essentials of Anatomy & Physiology, Structure and Function of the Human Body, and The Human Body in Health and Disease (all published by Pearson).

    Mr. Bartholomew is a member of the Human Anatomy and Physiology Society (HAPS), the National Association of Biology Teachers, the National Science Teachers Association, the American Association for the Advancement of Science, and Lahaina Arts Society. He also enjoys painting in oil, watercolor, and pastels, as well as growing tropical fish, aquarium plants, and orchids.

  • William C. Ober, M.D. Author Bio

    Dr. Ober received his undergraduate degree from Washington and Lee University and his M.D. from the University of Virginia. He also studied in the Department of Art as Applied to Medicine at Johns Hopkins University.

    After graduation, Dr. Ober completed a residency in Family Practice and later was on the faculty at the University of Virginia in the Department of Family Medicine and in the Department of Sports Medicine. He also served as Chief of Medicine of Martha Jefferson Hospital in Charlottesville, Virginia.

    Most recently he was Visiting Professor of Biology at Washington and Lee University, where he taught courses in biological illustration and led student trips to the Galapagos Islands. He was on the Core Faculty at Shoals Marine Laboratory for 24 years, where he taught biological illustration every summer. Dr. Ober has collaborated with Dr. Martini on all his textbooks in every edition.

  • Claire E. Ober, R.N. Author Bio

    Claire E. Ober, R.N., B.A., practiced family, pediatric, and obstetric nursing before turning to medical illustration as a full-time career. She returned to school at Mary Baldwin College, where she received her degree with distinction in studio art.

    Following a 5-year apprenticeship, she has worked as Dr. Ober’s partner in Medical & Scientific Illustration since 1986. She was on the Core Faculty at Shoals Marine Laboratory and co-taught the biological illustration course with Dr. Ober for 24 years. The textbooks illustrated by Medical & Scientific Illustration have won numerous design and illustration awards.

  • Table of Contents


    • An Introduction to Anatomy and Physiology
    • The Chemical Level of Organization
    • The Cellular Level of Organization
    • The Tissue Level of Organization


    • The Integumentary System
    • Bones and Bone Structure
    • The Axial Skeleton
    • The Appendicular Skeleton
    • Joints
    • Muscle Tissue
    • The Muscular System


    • Nervous Tissue
    • The Spinal Cord, Spinal Nerves and Spinal Reflexes
    • The Brain and Cranial Nerves
    • Sensory Pathways and the Somatic Nervous System
    • The Autonomic Nervous System and Higher Order Functions
    • The Special Senses
    • The Endocrine System


    • Blood
    • The Heart
    • Blood Vessels and Circulation
    • The Lymphatic System and Immunity


    • The Respiratory System
    • The Digestive System
    • Metabolism, Nutrition and Energetics
    • The Urinary System
    • Fluid, Electrolyte and Acid-Base Balance


    • The Reproductive System
    • Development and Inheritance


    • Normal Physiological Values
    • Gas Pressure Measurements
    • Turnover Times for Selected Cells
    • Codon Chart
    • The Periodic Table
    • Common Abbreviations Used in Science
    • Word Roots, Prefixes, Suffixes, And Combining Forms

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